GrippeEspagneV1, Main, Exploration, bibRecord, 000071

Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010-2015).

Identifieur interne : 000071 ( Main/Exploration ); précédent : 000070; suivant : 000072

Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010-2015).

Auteurs : Núria Torner [Espagne] ; Ana Martínez [Espagne] ; Luca Basile [Espagne] ; Mmar Mosquera [Espagne] ; Andrés Ant N [Espagne] ; Cristina Rius [Espagne] ; M Rosa Sala [Espagne] ; Sofia Minguell [Espagne] ; Elsa Plasencia [Espagne] ; M Nica Carol [Espagne] ; Pere Godoy [Espagne] ; Núria Follia [Espagne] ; Irene Barrabeig [Espagne] ; M Angeles Marcos [Espagne] ; Tomàs Pumarola [Espagne] ; Mireia Jané [Espagne]

Source :

BMC research notes [ 1756-0500 ] ; 2018.

RBID : pubmed:29655370

Descripteurs français

KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Adulte d'âge moyen (MeSH), Antiviraux (usage thérapeutique), Enfant (MeSH), Enfant d'âge préscolaire (MeSH), Espagne (épidémiologie), Femelle (MeSH), Grippe humaine (mortalité), Grippe humaine (traitement médicamenteux), Grippe humaine (virologie), Grippe humaine (épidémiologie), Hospitalisation (statistiques et données numériques), Humains (MeSH), Jeune adulte (MeSH), Mâle (MeSH), Nourrisson (MeSH), Sous-type H1N1 du virus de la grippe A (isolement et purification), Sous-type H3N2 du virus de la grippe A (isolement et purification), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Surveillance sentinelle (MeSH), Épidémies (statistiques et données numériques).
MESH :
- isolement et purification : Sous-type H1N1 du virus de la grippe A, Sous-type H3N2 du virus de la grippe A.
- mortalité : Grippe humaine.
- statistiques et données numériques : Hospitalisation, Épidémies.
- traitement médicamenteux : Grippe humaine.
- usage thérapeutique : Antiviraux.
- virologie : Grippe humaine.
- épidémiologie : Espagne, Grippe humaine.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Femelle, Humains, Jeune adulte, Mâle, Nourrisson, Sujet âgé, Sujet âgé de 80 ans ou plus, Surveillance sentinelle.

English descriptors

KwdEn :
- Adolescent (MeSH), Adult (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), Antiviral Agents (therapeutic use), Child (MeSH), Child, Preschool (MeSH), Epidemics (statistics & numerical data), Female (MeSH), Hospitalization (statistics & numerical data), Humans (MeSH), Infant (MeSH), Influenza A Virus, H1N1 Subtype (isolation & purification), Influenza A Virus, H3N2 Subtype (isolation & purification), Influenza, Human (drug therapy), Influenza, Human (epidemiology), Influenza, Human (mortality), Influenza, Human (virology), Male (MeSH), Middle Aged (MeSH), Sentinel Surveillance (MeSH), Spain (epidemiology), Young Adult (MeSH).
MESH :
- chemical , therapeutic use : Antiviral Agents.
- drug therapy : Influenza, Human.
- epidemiology : Influenza, Human, Spain.
- isolation & purification : Influenza A Virus, H1N1 Subtype, Influenza A Virus, H3N2 Subtype.
- mortality : Influenza, Human.
- statistics & numerical data : Epidemics, Hospitalization.
- virology : Influenza, Human.
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Humans, Infant, Male, Middle Aged, Sentinel Surveillance, Young Adult.

Abstract

OBJECTIVE

The Plan of Information on Acute Respiratory Infections in Catalonia (PIDIRAC) included the surveillance of severe hospitalized cases of laboratory-confirmed influenza (SHCLCI) in 2009. The objective of this study was to determine the clinical, epidemiological and virological features of SHCLCI recorded in 12 sentinel hospitals during five influenza seasons.

RESULTS

From a sample of SHCLCI recorded during the 5 influenza epidemics seasons from 2010-2011 to 2014-2015, Cases were confirmed by PCR and/or viral isolation in cell cultures from respiratory samples. A total of 1400 SHCLCI were recorded, 33% required ICU admission and 12% died. The median age of cases was 61 years (range 0-101 years); 70.5% were unvaccinated; 80.4% received antiviral treatment (in 79.6 and 24% of cases within 48 h after hospital admission and the onset of symptoms, respectively); influenza virus A [37.9% A (H1N1)pdm09, 29.3% A (H3N2)] was identified in 87.7% of cases. Surveillance of SHCLCI provides an estimate of the severity of seasonal influenza epidemics and the identification and characterization of at-risk groups in order to facilitate preventive measures such as vaccination and early antiviral treatment.

DOI: 10.1186/s13104-018-3349-y
PubMed: 29655370
PubMed Central: PMC5899835

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 00056
to stream Main, to step Curation: 000056

Le document en format XML

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<author><name sortKey="Rius, Cristina" sort="Rius, Cristina" uniqKey="Rius C" first="Cristina" last="Rius">Cristina Rius</name>
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<author><name sortKey="Minguell, Sofia" sort="Minguell, Sofia" uniqKey="Minguell S" first="Sofia" last="Minguell">Sofia Minguell</name>
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<author><name sortKey="Plasencia, Elsa" sort="Plasencia, Elsa" uniqKey="Plasencia E" first="Elsa" last="Plasencia">Elsa Plasencia</name>
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<author><name sortKey="Carol, M Nica" sort="Carol, M Nica" uniqKey="Carol M" first="M Nica" last="Carol">M Nica Carol</name>
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<author><name sortKey="Godoy, Pere" sort="Godoy, Pere" uniqKey="Godoy P" first="Pere" last="Godoy">Pere Godoy</name>
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<author><name sortKey="Follia, Nuria" sort="Follia, Nuria" uniqKey="Follia N" first="Núria" last="Follia">Núria Follia</name>
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<author><name sortKey="Barrabeig, Irene" sort="Barrabeig, Irene" uniqKey="Barrabeig I" first="Irene" last="Barrabeig">Irene Barrabeig</name>
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<author><name sortKey="Marcos, M Angeles" sort="Marcos, M Angeles" uniqKey="Marcos M" first="M Angeles" last="Marcos">M Angeles Marcos</name>
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<author><name sortKey="Pumarola, Tomas" sort="Pumarola, Tomas" uniqKey="Pumarola T" first="Tomàs" last="Pumarola">Tomàs Pumarola</name>
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<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Microbiology Department, Hospital Universitari Vall d'Hebron de Barcelona, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
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</placeName>
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</author>
<author><name sortKey="Jane, Mireia" sort="Jane, Mireia" uniqKey="Jane M" first="Mireia" last="Jané">Mireia Jané</name>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
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<idno type="doi">10.1186/s13104-018-3349-y</idno>
<idno type="pmc">PMC5899835</idno>
<idno type="wicri:Area/Main/Corpus">00056</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010-2015).</title>
<author><name sortKey="Torner, Nuria" sort="Torner, Nuria" uniqKey="Torner N" first="Núria" last="Torner">Núria Torner</name>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain. nuria.torner@gencat.cat.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid, Spain. nuria.torner@gencat.cat.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Departament of Public Health, University of Barcelona, Barcelona, Spain. nuria.torner@gencat.cat.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Departament of Public Health, University of Barcelona, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Martinez, Ana" sort="Martinez, Ana" uniqKey="Martinez A" first="Ana" last="Martínez">Ana Martínez</name>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
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<author><name sortKey="Basile, Luca" sort="Basile, Luca" uniqKey="Basile L" first="Luca" last="Basile">Luca Basile</name>
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<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mosquera, Mmar" sort="Mosquera, Mmar" uniqKey="Mosquera M" first="Mmar" last="Mosquera">Mmar Mosquera</name>
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<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Microbiology Department, Hospital Clínic de Barcelona, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ant N, Andres" sort="Ant N, Andres" uniqKey="Ant N A" first="Andrés" last="Ant N">Andrés Ant N</name>
<affiliation wicri:level="3"><nlm:affiliation>Microbiology Department, Hospital Universitari Vall d'Hebron de Barcelona, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Microbiology Department, Hospital Universitari Vall d'Hebron de Barcelona, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
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<author><name sortKey="Rius, Cristina" sort="Rius, Cristina" uniqKey="Rius C" first="Cristina" last="Rius">Cristina Rius</name>
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<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Agency of Barcelona, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Agency of Barcelona, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sala, M Rosa" sort="Sala, M Rosa" uniqKey="Sala M" first="M Rosa" last="Sala">M Rosa Sala</name>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Minguell, Sofia" sort="Minguell, Sofia" uniqKey="Minguell S" first="Sofia" last="Minguell">Sofia Minguell</name>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Plasencia, Elsa" sort="Plasencia, Elsa" uniqKey="Plasencia E" first="Elsa" last="Plasencia">Elsa Plasencia</name>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
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</author>
<author><name sortKey="Carol, M Nica" sort="Carol, M Nica" uniqKey="Carol M" first="M Nica" last="Carol">M Nica Carol</name>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Godoy, Pere" sort="Godoy, Pere" uniqKey="Godoy P" first="Pere" last="Godoy">Pere Godoy</name>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Follia, Nuria" sort="Follia, Nuria" uniqKey="Follia N" first="Núria" last="Follia">Núria Follia</name>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Barrabeig, Irene" sort="Barrabeig, Irene" uniqKey="Barrabeig I" first="Irene" last="Barrabeig">Irene Barrabeig</name>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Marcos, M Angeles" sort="Marcos, M Angeles" uniqKey="Marcos M" first="M Angeles" last="Marcos">M Angeles Marcos</name>
<affiliation wicri:level="3"><nlm:affiliation>Microbiology Department, Hospital Clínic de Barcelona, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Microbiology Department, Hospital Clínic de Barcelona, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pumarola, Tomas" sort="Pumarola, Tomas" uniqKey="Pumarola T" first="Tomàs" last="Pumarola">Tomàs Pumarola</name>
<affiliation wicri:level="3"><nlm:affiliation>Microbiology Department, Hospital Universitari Vall d'Hebron de Barcelona, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Microbiology Department, Hospital Universitari Vall d'Hebron de Barcelona, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jane, Mireia" sort="Jane, Mireia" uniqKey="Jane M" first="Mireia" last="Jané">Mireia Jané</name>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">BMC research notes</title>
<idno type="eISSN">1756-0500</idno>
<imprint><date when="2018" type="published">2018</date>
</imprint>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term>
<term>Adult (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Aged, 80 and over (MeSH)</term>
<term>Antiviral Agents (therapeutic use)</term>
<term>Child (MeSH)</term>
<term>Child, Preschool (MeSH)</term>
<term>Epidemics (statistics & numerical data)</term>
<term>Female (MeSH)</term>
<term>Hospitalization (statistics & numerical data)</term>
<term>Humans (MeSH)</term>
<term>Infant (MeSH)</term>
<term>Influenza A Virus, H1N1 Subtype (isolation & purification)</term>
<term>Influenza A Virus, H3N2 Subtype (isolation & purification)</term>
<term>Influenza, Human (drug therapy)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (mortality)</term>
<term>Influenza, Human (virology)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Sentinel Surveillance (MeSH)</term>
<term>Spain (epidemiology)</term>
<term>Young Adult (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term>
<term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Antiviraux (usage thérapeutique)</term>
<term>Enfant (MeSH)</term>
<term>Enfant d'âge préscolaire (MeSH)</term>
<term>Espagne (épidémiologie)</term>
<term>Femelle (MeSH)</term>
<term>Grippe humaine (mortalité)</term>
<term>Grippe humaine (traitement médicamenteux)</term>
<term>Grippe humaine (virologie)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Hospitalisation (statistiques et données numériques)</term>
<term>Humains (MeSH)</term>
<term>Jeune adulte (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Nourrisson (MeSH)</term>
<term>Sous-type H1N1 du virus de la grippe A (isolement et purification)</term>
<term>Sous-type H3N2 du virus de la grippe A (isolement et purification)</term>
<term>Sujet âgé (MeSH)</term>
<term>Sujet âgé de 80 ans ou plus (MeSH)</term>
<term>Surveillance sentinelle (MeSH)</term>
<term>Épidémies (statistiques et données numériques)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term>
<term>Spain</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A Virus, H1N1 Subtype</term>
<term>Influenza A Virus, H3N2 Subtype</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Sous-type H1N1 du virus de la grippe A</term>
<term>Sous-type H3N2 du virus de la grippe A</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Epidemics</term>
<term>Hospitalization</term>
</keywords>
<keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Hospitalisation</term>
<term>Épidémies</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Espagne</term>
<term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Female</term>
<term>Humans</term>
<term>Infant</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Sentinel Surveillance</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Femelle</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Nourrisson</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Surveillance sentinelle</term>
</keywords>
</textClass>
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</teiHeader>
<front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b>
</p>
<p>The Plan of Information on Acute Respiratory Infections in Catalonia (PIDIRAC) included the surveillance of severe hospitalized cases of laboratory-confirmed influenza (SHCLCI) in 2009. The objective of this study was to determine the clinical, epidemiological and virological features of SHCLCI recorded in 12 sentinel hospitals during five influenza seasons.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>From a sample of SHCLCI recorded during the 5 influenza epidemics seasons from 2010-2011 to 2014-2015, Cases were confirmed by PCR and/or viral isolation in cell cultures from respiratory samples. A total of 1400 SHCLCI were recorded, 33% required ICU admission and 12% died. The median age of cases was 61 years (range 0-101 years); 70.5% were unvaccinated; 80.4% received antiviral treatment (in 79.6 and 24% of cases within 48 h after hospital admission and the onset of symptoms, respectively); influenza virus A [37.9% A (H1N1)pdm09, 29.3% A (H3N2)] was identified in 87.7% of cases. Surveillance of SHCLCI provides an estimate of the severity of seasonal influenza epidemics and the identification and characterization of at-risk groups in order to facilitate preventive measures such as vaccination and early antiviral treatment.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29655370</PMID>
<DateCompleted><Year>2018</Year>
<Month>10</Month>
<Day>01</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>11</Month>
<Day>14</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1756-0500</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>11</Volume>
<Issue>1</Issue>
<PubDate><Year>2018</Year>
<Month>Apr</Month>
<Day>14</Day>
</PubDate>
</JournalIssue>
<Title>BMC research notes</Title>
<ISOAbbreviation>BMC Res Notes</ISOAbbreviation>
</Journal>
<ArticleTitle>Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010-2015).</ArticleTitle>
<Pagination><MedlinePgn>244</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1186/s13104-018-3349-y</ELocationID>
<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The Plan of Information on Acute Respiratory Infections in Catalonia (PIDIRAC) included the surveillance of severe hospitalized cases of laboratory-confirmed influenza (SHCLCI) in 2009. The objective of this study was to determine the clinical, epidemiological and virological features of SHCLCI recorded in 12 sentinel hospitals during five influenza seasons.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">From a sample of SHCLCI recorded during the 5 influenza epidemics seasons from 2010-2011 to 2014-2015, Cases were confirmed by PCR and/or viral isolation in cell cultures from respiratory samples. A total of 1400 SHCLCI were recorded, 33% required ICU admission and 12% died. The median age of cases was 61 years (range 0-101 years); 70.5% were unvaccinated; 80.4% received antiviral treatment (in 79.6 and 24% of cases within 48 h after hospital admission and the onset of symptoms, respectively); influenza virus A [37.9% A (H1N1)pdm09, 29.3% A (H3N2)] was identified in 87.7% of cases. Surveillance of SHCLCI provides an estimate of the severity of seasonal influenza epidemics and the identification and characterization of at-risk groups in order to facilitate preventive measures such as vaccination and early antiviral treatment.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Torner</LastName>
<ForeName>Núria</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain. nuria.torner@gencat.cat.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid, Spain. nuria.torner@gencat.cat.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Departament of Public Health, University of Barcelona, Barcelona, Spain. nuria.torner@gencat.cat.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Martínez</LastName>
<ForeName>Ana</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Basile</LastName>
<ForeName>Luca</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mosquera</LastName>
<ForeName>MMar</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Microbiology Department, Hospital Clínic de Barcelona, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Antón</LastName>
<ForeName>Andrés</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Microbiology Department, Hospital Universitari Vall d'Hebron de Barcelona, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Rius</LastName>
<ForeName>Cristina</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Public Health Agency of Barcelona, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sala</LastName>
<ForeName>M Rosa</ForeName>
<Initials>MR</Initials>
<AffiliationInfo><Affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Minguell</LastName>
<ForeName>Sofia</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Plasencia</LastName>
<ForeName>Elsa</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Carol</LastName>
<ForeName>Mónica</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Godoy</LastName>
<ForeName>Pere</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Follia</LastName>
<ForeName>Núria</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Barrabeig</LastName>
<ForeName>Irene</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Marcos</LastName>
<ForeName>M Angeles</ForeName>
<Initials>MA</Initials>
<AffiliationInfo><Affiliation>Microbiology Department, Hospital Clínic de Barcelona, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pumarola</LastName>
<ForeName>Tomàs</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Microbiology Department, Hospital Universitari Vall d'Hebron de Barcelona, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jané</LastName>
<ForeName>Mireia</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Public Health Agency of Catalonia, Roc Boronat, 81-95, 08005, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>CIBER Epidemiologia y Salud Pública CIBERESP, Madrid, Spain.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2018</Year>
<Month>04</Month>
<Day>14</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>BMC Res Notes</MedlineTA>
<NlmUniqueID>101462768</NlmUniqueID>
<ISSNLinking>1756-0500</ISSNLinking>
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<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000998">Antiviral Agents</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
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</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName>
</MeshHeading>
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<MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName>
</MeshHeading>
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</MeshHeading>
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<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D053122" MajorTopicYN="N">Influenza A Virus, H3N2 Subtype</DescriptorName>
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<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
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<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018571" MajorTopicYN="Y">Sentinel Surveillance</DescriptorName>
</MeshHeading>
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<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Antiviral drugs</Keyword>
<Keyword MajorTopicYN="N">Epidemiology</Keyword>
<Keyword MajorTopicYN="N">Influenza</Keyword>
<Keyword MajorTopicYN="N">Surveillance</Keyword>
<Keyword MajorTopicYN="N">Vaccine</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year>
<Month>01</Month>
<Day>15</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2018</Year>
<Month>04</Month>
<Day>06</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2018</Year>
<Month>4</Month>
<Day>16</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<Day>16</Day>
<Hour>6</Hour>
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<PubMedPubDate PubStatus="medline"><Year>2018</Year>
<Month>10</Month>
<Day>3</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010-2015).

Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010-2015).

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